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Administrarea Imovane impreuna cu buprenorfina sau cu medicamente barbiturice creste riscul de deprimare respiratorie, care poate avea efect letal.   Stosowanie leków uspokajających i nasennych o działaniu podobnym do benzodiazepin może prowadzić do rozwoju uzależnienia. Ryzyko wystąpienia uzależnienia zwiększa się wraz z wielkości

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